Application of DTI connectivity in lateralization of mTLE
Autor: | Mohammad R. Nazem-Zadeh, Esmaeil Davoodi-Bojd, Fariborz Mahmoudi, Susan M. Bowyer, John E. Moran, Hassan Bagher-Ebadian, Andrew Zillgitt, Kost Elisevich, Hamid Soltanian-Zadeh |
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Rok vydání: | 2016 |
Předmět: |
Adult
Male Precuneus Insular cortex Models Biological behavioral disciplines and activities Article Functional Laterality Lateralization of brain function 030218 nuclear medicine & medical imaging White matter 03 medical and health sciences Epilepsy Superior temporal gyrus 0302 clinical medicine Parietal Lobe medicine Humans Cerebral Cortex Anatomy medicine.disease White Matter Temporal Lobe Frontal Lobe Diffusion Tensor Imaging medicine.anatomical_structure Epilepsy Temporal Lobe nervous system Case-Control Studies Laterality Female Psychology Neuroscience psychological phenomena and processes 030217 neurology & neurosurgery Diffusion MRI |
Zdroj: | EMBC |
DOI: | 10.1109/embc.2016.7591978 |
Popis: | Diffusion tensor imaging (DTI) is a noninvasive imaging method for measuring the diffusion properties of the underlying white matter tracts through which epileptiform activity is propagated. This study investigates the structural abnormalities quantified by DTI in mesial temporal lobe epilepsy (mTLE). Fiber tracts passing through 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender- matched controls were identified using DTI tractography. DTI nodal degree (ND) and laterality index were then calculated. ND laterality, after Bonferroni adjustment, showed significant differences for right versus left mTLE in gyrus rectus, insular cortex, precuneus and superior temporal gyrus (p |
Databáze: | OpenAIRE |
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