The microbiome and its impact on food allergy and atopic dermatitis in children

Autor: Tomasz Grzybowski, Urszula Rogalla-Ładniak, Aneta Krogulska, Ewa Łoś-Rycharska, Marcin Gołębiewski
Rok vydání: 2020
Předmět:
Zdroj: Advances in Dermatology and Allergology, Vol 37, Iss 5, Pp 641-650 (2020)
Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
ISSN: 1642-395X
DOI: 10.5114/ada.2019.90120
Popis: Food allergy (FA) affects 4–10% of children, especially children with atopic dermatitis (AD). During infancy the gut microbiome may determine both the course of FA and tolerance to food allergens. Analogically, the skin microbiome changes in the course of AD. Most studies have associated FA with a lower abundance and diversity of Lactobacillales and Clostridiales, but greater numbers of Enterobacterales, while AD in children has been associated with lower numbers of Staphylococcus epidermidis and S. hominis but an abundance of S. aureus and Streptococcus species. An understanding of the impact of the microbiome on the clinical course of FA and AD may allow for the development of new models of allergy treatment and prevention.
Databáze: OpenAIRE
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