The microbiome and its impact on food allergy and atopic dermatitis in children
| Autor: | Tomasz Grzybowski, Urszula Rogalla-Ładniak, Aneta Krogulska, Ewa Łoś-Rycharska, Marcin Gołębiewski |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Allergy
microbiome Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Staphylococcus epidermidis Food allergy medicine infants Immunology and Allergy Microbiome Internal medicine Review Paper food allergy atopic dermatitis biology business.industry Lactobacillales Clostridiales Atopic dermatitis medicine.disease biology.organism_classification RC31-1245 Gut microbiome RL1-803 Immunology business |
| Zdroj: | Advances in Dermatology and Allergology, Vol 37, Iss 5, Pp 641-650 (2020) Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii |
| ISSN: | 1642-395X |
| DOI: | 10.5114/ada.2019.90120 |
| Popis: | Food allergy (FA) affects 4–10% of children, especially children with atopic dermatitis (AD). During infancy the gut microbiome may determine both the course of FA and tolerance to food allergens. Analogically, the skin microbiome changes in the course of AD. Most studies have associated FA with a lower abundance and diversity of Lactobacillales and Clostridiales, but greater numbers of Enterobacterales, while AD in children has been associated with lower numbers of Staphylococcus epidermidis and S. hominis but an abundance of S. aureus and Streptococcus species. An understanding of the impact of the microbiome on the clinical course of FA and AD may allow for the development of new models of allergy treatment and prevention. |
| Databáze: | OpenAIRE |
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