Prevalence, clinicopathological features, and prognosis in upper tract urinary carcinoma patients with severe preoperative chronic kidney disease

Autor: Yicong Du, Liqun Zhou, Yonghao Zhan, Gengyan Xiong, Dong Fang, Cheng Qian, Xuesong Li, Zhengqing Bao, Lei Zhang, Yuze Zhu, Yiming Yuan
Rok vydání: 2019
Předmět:
Zdroj: Translational Andrology and Urology. 8:641-650
ISSN: 2223-4691
2223-4683
DOI: 10.21037/tau.2019.11.19
Popis: BACKGROUND: Studies regarding the prevalence and factors associated with severe pre-operative chronic kidney disease (CKD) in upper tract urinary carcinoma (UTUC) patients were rare due to the low prevalence of UTUC. We conducted the present study to investigate the prevalence, clinicopathological features, and prognosis in UTUC patients with severe preoperative CKD. METHODS: The study included 731 patients with UTUC treated with radical nephroureterectomy (RNU) in a large Chinese center. Estimated glomerular filtration rate (eGFR) was calculated by re-expressed Modification of Diet in Renal Disease (MDRD) formulas for the Chinese population. Severe preoperative CKD was defined as CKD stage 4–5 (eGFR
Databáze: OpenAIRE