Prevalence, clinicopathological features, and prognosis in upper tract urinary carcinoma patients with severe preoperative chronic kidney disease
Autor: | Yicong Du, Liqun Zhou, Yonghao Zhan, Gengyan Xiong, Dong Fang, Cheng Qian, Xuesong Li, Zhengqing Bao, Lei Zhang, Yuze Zhu, Yiming Yuan |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
business.industry Urology Urinary system 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology medicine.disease Gastroenterology 03 medical and health sciences 0302 clinical medicine Reproductive Medicine Internal medicine Concomitant Cohort medicine Carcinoma T-stage Original Article business Kidney disease Upper urinary tract |
Zdroj: | Translational Andrology and Urology. 8:641-650 |
ISSN: | 2223-4691 2223-4683 |
DOI: | 10.21037/tau.2019.11.19 |
Popis: | BACKGROUND: Studies regarding the prevalence and factors associated with severe pre-operative chronic kidney disease (CKD) in upper tract urinary carcinoma (UTUC) patients were rare due to the low prevalence of UTUC. We conducted the present study to investigate the prevalence, clinicopathological features, and prognosis in UTUC patients with severe preoperative CKD. METHODS: The study included 731 patients with UTUC treated with radical nephroureterectomy (RNU) in a large Chinese center. Estimated glomerular filtration rate (eGFR) was calculated by re-expressed Modification of Diet in Renal Disease (MDRD) formulas for the Chinese population. Severe preoperative CKD was defined as CKD stage 4–5 (eGFR |
Databáze: | OpenAIRE |
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