Evaluation of antibiotic use in intensive care units of a tertiary care hospital in Turkey
Autor: | Esragül Akinci, Hurrem Bodur, Ayşe Erbay, Aylin Çolpan |
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Rok vydání: | 2005 |
Předmět: |
Male
Microbiology (medical) medicine.medical_specialty Turkey Referral medicine.drug_class Antibiotics Drug Prescriptions Drug Costs law.invention Drug Utilization Review law Intensive care Ampicillin Drug Resistance Bacterial medicine Humans Prospective Studies Practice Patterns Physicians' Medical prescription Intensive care medicine APACHE Antibacterial agent Academic Medical Centers Cross Infection Information Dissemination business.industry Patient Selection General Medicine Sulbactam Middle Aged Intensive care unit Organizational Policy Anti-Bacterial Agents Intensive Care Units Logistic Models Infectious Diseases Practice Guidelines as Topic Emergency medicine Education Medical Continuing Female Guideline Adherence business Needs Assessment Total Quality Management medicine.drug |
Zdroj: | Journal of Hospital Infection. 59:53-61 |
ISSN: | 0195-6701 |
DOI: | 10.1016/j.jhin.2004.07.026 |
Popis: | The object of this study was to evaluate the appropriateness of antibiotic use in relation to diagnosis and bacteriological findings in the intensive care units (ICUs) of a 1100-bed referral and tertiary care hospital with an antibiotic restriction policy in Turkey. Between June and December 2002, patients who received antibiotics in the medical and surgical ICUs were evaluated prospectively. Two infectious diseases (ID) specialists assessed the antibiotics ordered daily. Of the 368 patients admitted to the ICUs, 223 (60.6%) received 440 antibiotics. The most frequently prescribed antibiotics were first-generation cephalosporins (16.1%), third-generation cephalosporins (15.2%), aminoglycosides (12.1%), carbapenems (10.7%) and ampicillin-sulbactam (8.7%). Antibiotic use was inappropriate in 47.3% of antibiotics. ID specialists recommended the use of 47% of all antibiotics. An antibiotic order without an ID consultation was more likely to be inappropriate [odds ratio (OR)=13.2, P |
Databáze: | OpenAIRE |
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