Evaluation of antibiotic use in intensive care units of a tertiary care hospital in Turkey

Autor: Esragül Akinci, Hurrem Bodur, Ayşe Erbay, Aylin Çolpan
Rok vydání: 2005
Předmět:
Zdroj: Journal of Hospital Infection. 59:53-61
ISSN: 0195-6701
DOI: 10.1016/j.jhin.2004.07.026
Popis: The object of this study was to evaluate the appropriateness of antibiotic use in relation to diagnosis and bacteriological findings in the intensive care units (ICUs) of a 1100-bed referral and tertiary care hospital with an antibiotic restriction policy in Turkey. Between June and December 2002, patients who received antibiotics in the medical and surgical ICUs were evaluated prospectively. Two infectious diseases (ID) specialists assessed the antibiotics ordered daily. Of the 368 patients admitted to the ICUs, 223 (60.6%) received 440 antibiotics. The most frequently prescribed antibiotics were first-generation cephalosporins (16.1%), third-generation cephalosporins (15.2%), aminoglycosides (12.1%), carbapenems (10.7%) and ampicillin-sulbactam (8.7%). Antibiotic use was inappropriate in 47.3% of antibiotics. ID specialists recommended the use of 47% of all antibiotics. An antibiotic order without an ID consultation was more likely to be inappropriate [odds ratio (OR)=13.2, P
Databáze: OpenAIRE