Nationwide Survey of Pediatric Inpatients With Hand, Foot, and Mouth Disease, Herpangina, and Associated Complications During an Epidemic Period in Japan: Estimated Number of Hospitalized Patients and Factors Associated With Severe Cases
Autor: | Kazuya Ito, Hiroyuki Shimizu, Takashi Nakano, Kyoko Kondo, Tetsuo Kase, Wakaba Fukushima, Akiko Maeda, Yoshio Hirota, Maria Takechi, Satoko Ohfuji, Miki Inui |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Male
Herpangina medicine.medical_specialty Pediatrics Adolescent Epidemiology Population hand foot and mouth disease 030209 endocrinology & metabolism Severity of Illness Index 03 medical and health sciences nationwide survey 0302 clinical medicine Japan Risk Factors pediatric hospitalization Surveys and Questionnaires medicine Enterovirus 71 Humans Clinical Epidemiology Cumulative incidence 030212 general & internal medicine Child Epidemics education enterovirus 71 Disease burden education.field_of_study lcsh:R5-920 biology business.industry Infant Newborn Infant General Medicine Odds ratio medicine.disease biology.organism_classification Confidence interval Hospitalization Child Preschool Original Article Female Hand Foot and Mouth Disease business lcsh:Medicine (General) |
Zdroj: | Journal of Epidemiology, Vol 29, Iss 9, Pp 354-362 (2019) Journal of Epidemiology |
ISSN: | 1349-9092 0917-5040 |
Popis: | Background: Severe pediatric cases of hand, foot, and mouth disease (HFMD), herpangina (HA), and associated complications caused by enterovirus 71 (EV71) infection have brought substantial public health impact in Asia. This study aimed to elucidate the epidemiology of these pediatric cases in Japan. Methods: A nationwide survey was conducted using stratified random sampling of hospital pediatric departments. We estimated the number of inpatients with HFMD, HA, and associated complications between April 1 and September 30, 2010, during which EV71 was circulating predominantly. Factors associated with severe cases with ≥7 days of admission, sequelae, or outcome of death were analyzed using multivariate logistic regression. Results: During the 6-month epidemic period, the number of pediatric inpatients aged |
Databáze: | OpenAIRE |
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