Nationwide Survey of Pediatric Inpatients With Hand, Foot, and Mouth Disease, Herpangina, and Associated Complications During an Epidemic Period in Japan: Estimated Number of Hospitalized Patients and Factors Associated With Severe Cases

Autor: Kazuya Ito, Hiroyuki Shimizu, Takashi Nakano, Kyoko Kondo, Tetsuo Kase, Wakaba Fukushima, Akiko Maeda, Yoshio Hirota, Maria Takechi, Satoko Ohfuji, Miki Inui
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Epidemiology, Vol 29, Iss 9, Pp 354-362 (2019)
Journal of Epidemiology
ISSN: 1349-9092
0917-5040
Popis: Background: Severe pediatric cases of hand, foot, and mouth disease (HFMD), herpangina (HA), and associated complications caused by enterovirus 71 (EV71) infection have brought substantial public health impact in Asia. This study aimed to elucidate the epidemiology of these pediatric cases in Japan. Methods: A nationwide survey was conducted using stratified random sampling of hospital pediatric departments. We estimated the number of inpatients with HFMD, HA, and associated complications between April 1 and September 30, 2010, during which EV71 was circulating predominantly. Factors associated with severe cases with ≥7 days of admission, sequelae, or outcome of death were analyzed using multivariate logistic regression. Results: During the 6-month epidemic period, the number of pediatric inpatients aged
Databáze: OpenAIRE
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