Clinicopathologic features between different viral epidemic outbreaks involving the skin
| Autor: | Snejina Vassileva, Caterina Ferreli, Laura Atzori, Valeria Mateeva, Franco Rongioletti |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
COVID-19 coronavirus 2019 disease DENGV Dengue virus MERS Middle East Respiratory Syndrome Mucocutaneous zone ACE-2 Angiotensin‐converting enzyme 2 vWF von Willebrand factor Dermatology Disease pandemics IgA immunoglobulin A ZIKV Zika virus clinico-pathologic correlation WHO World Health Organization Article epidemics Disease Outbreaks Dengue fever skin manifestations 030207 dermatology & venereal diseases 03 medical and health sciences RT-PCR reverse transcription polymerase chain reaction 0302 clinical medicine Pathognomonic Pandemic Humans Medicine E1 E2 envelope glycoprotein Intensive care medicine Skin 030203 arthritis & rheumatology Sars-Cov-2 novel coronavirus SARS-CoV-2 business.industry CD1a cluster of diffentiation 1-a COVID-19 Outbreak IFN-I interferon-type-I CHIKV Chikungunya virus medicine.disease R0 basic reproductive number SARS severe acute respiratory syndrome coronavirus TTP thrombotic thrombocytopenic purpura MIS multisystem inflammatory syndrome Middle East respiratory syndrome EBOV Ebola virus Differential diagnosis business |
| Zdroj: | Clinics in Dermatology |
| ISSN: | 0738-081X |
| DOI: | 10.1016/j.clindermatol.2021.04.002 |
| Popis: | The current coronavirus disease 2019 pandemic has exceeded any epidemiologic prevision, but increasing information suggests some analogies with the major viral outbreaks in the last century, and a general warning has been issued on the possibility that coinfections can make the differential diagnosis and treatment difficult, especially in tropical countries. Some reports have noted that the presence of high dengue antibodies can give a false-negative result when testing for severe acute respiratory syndrome coronavirus 2. Mucocutaneous manifestations are very frequent, with an apparent overlap among different pathogens. However, strong clinicopathologic correlation might provide some clues to address differentials. Waiting for laboratory and instrumental results, the timing and distribution of skin lesions is often pathognomonic. Histopathologic findings characterize certain reaction patterns and provide insights on pathogenetic mechanisms. Unfortunately, skin assessment, especially invasive examinations such as biopsy, takes a back seat in severely ill patients. A literature retrieval was performed to collect information from other epidemics to counteract what has become the most frightening disease of our time. |
| Databáze: | OpenAIRE |
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