HLA-G 5′ URR SNPs and 3′ UTR 14-bp insertion/deletion polymorphism in an Afro-Brazilian population from Paraná State

Autor:	L. C. Santos, Joandrei dos Santos Silva, João Carlos M. Magalhães, Luciane Viater Tureck, S. B. Mattar, Pryscilla Fanini Wowk, Maria da Graça Bicalho, Valéria Maria Munhoz Sperandio Roxo
Rok vydání:	2013
Předmět:	Male Genotype Immunology Population Single-nucleotide polymorphism Human leukocyte antigen Biology Polymorphism Single Nucleotide Gene Frequency INDEL Mutation stomatognathic system Polymorphism (computer science) HLA-G parasitic diseases Ethnicity Genetics Humans education 3' Untranslated Regions Molecular Biology Alleles Genetics (clinical) HLA-G Antigens education.field_of_study Three prime untranslated region Haplotype Promoter General Medicine Genetics Population Haplotypes Female 5' Untranslated Regions Brazil geographic locations
Zdroj:	International Journal of Immunogenetics. 41:29-33
ISSN:	1744-3121
DOI:	10.1111/iji.12068
Popis:	Summary The present study investigated 23 SNPs in the 5′URR promoter region and the 14 bp ins/del polymorphism at the 3′UTR region of the HLA-G gene in 150 individuals with Afro-Brazilian ancestry. Three haplotypes were found to be the most frequent. Comparing these polymorphisms in other samples, our data suggest that Afro-Brazilians are more similar to the Euro-Brazilians than to Hutterite population.
Databáze:	OpenAIRE
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