Using the Initial Systolic Time Interval to assess cardiac autonomic function in Parkinson's disease
| Autor: | Sanne Boesveldt, Jan H. Meijer, Eskeline Elbertse, Rudolph M. Verdaasdonk, Henk W. Berendse |
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| Přispěvatelé: | Physics and medical technology, Neurology, NCA - Neurodegeneration, Neuroscience Campus Amsterdam - Neurodegeneration |
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Autonomic function
medicine.medical_specialty Sympathetic nervous system Parkinson's disease Multifunction cardiogram Biomedical Engineering Biophysics Diaphragmatic breathing Stimulus (physiology) Internal medicine medicine cardiac autonomic function lcsh:R5-920 Impedance cardiography medicine.diagnostic_test business.industry Initial systolic time interval medicine.disease medicine.anatomical_structure Systolic time intervals Parkinson’s disease Physical therapy Cardiology lcsh:Medicine (General) business sympathetic function |
| Zdroj: | Meijer, J H, Elberse, E, Boesveldt, S, Berendse, H W & Verdaasdonk, R M 2011, ' Using the Initial Systolic Time Interval to assess cardiac autonomic function in Parkinson's disease ', Journal of Electrical Bioimpedance, vol. 2, pp. 98-101 . https://doi.org/10.5617/jeb.216 Journal of Electrical Bioimpedance, Vol 2, Iss 1, Pp 98-101 (2011) Journal of Electrical Bioimpedance, 2, 98-101. Oslo Bioimpedance Group, Department of Physics, University of Oslo |
| ISSN: | 1891-5469 |
| Popis: | The Initial Systolic Time Interval (ISTI) has been defined as the time difference between the peak electrical and peak mechanical activity of the heart. ISTI is obtained from the electro-cardiogram and the impedance cardiogram. The response of ISTI while breathing at rest and to a deep breathing stimulus was studied in a group of patients suffering from Parkinson's disease (PD) and a group of healthy control subjects. ISTI showed substantial variability during these manoeuvres. The tests showed that the variability of RR and ISTI was substantially different between PD patients and controls. It is hypothesized that in PD patients the sympathetic system compensates for the loss of regulatory control function of the blood-pressure by the parasympathetic system. It is concluded that ISTI is a practical, additional and independent parameter that can be used to assist other tests in evaluating autonomic control of the heart in PD patients.doi:10.5617/jeb.216 J Electr Bioimp, vol. 2, pp. 98-101, 2011 |
| Databáze: | OpenAIRE |
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