Using the Initial Systolic Time Interval to assess cardiac autonomic function in Parkinson's disease

Autor: Sanne Boesveldt, Jan H. Meijer, Eskeline Elbertse, Rudolph M. Verdaasdonk, Henk W. Berendse
Přispěvatelé: Physics and medical technology, Neurology, NCA - Neurodegeneration, Neuroscience Campus Amsterdam - Neurodegeneration
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Meijer, J H, Elberse, E, Boesveldt, S, Berendse, H W & Verdaasdonk, R M 2011, ' Using the Initial Systolic Time Interval to assess cardiac autonomic function in Parkinson's disease ', Journal of Electrical Bioimpedance, vol. 2, pp. 98-101 . https://doi.org/10.5617/jeb.216
Journal of Electrical Bioimpedance, Vol 2, Iss 1, Pp 98-101 (2011)
Journal of Electrical Bioimpedance, 2, 98-101. Oslo Bioimpedance Group, Department of Physics, University of Oslo
ISSN: 1891-5469
Popis: The Initial Systolic Time Interval (ISTI) has been defined as the time difference between the peak electrical and peak mechanical activity of the heart. ISTI is obtained from the electro-cardiogram and the impedance cardiogram. The response of ISTI while breathing at rest and to a deep breathing stimulus was studied in a group of patients suffering from Parkinson's disease (PD) and a group of healthy control subjects. ISTI showed substantial variability during these manoeuvres. The tests showed that the variability of RR and ISTI was substantially different between PD patients and controls. It is hypothesized that in PD patients the sympathetic system compensates for the loss of regulatory control function of the blood-pressure by the parasympathetic system. It is concluded that ISTI is a practical, additional and independent parameter that can be used to assist other tests in evaluating autonomic control of the heart in PD patients.doi:10.5617/jeb.216 J Electr Bioimp, vol. 2, pp. 98-101, 2011
Databáze: OpenAIRE