Remodeling human osteoarthritic articular cartilage rAAV-mediated via combined gene transfer and overexpression of TGF-beta and sox9
Autor: | Tao, K, Frisch, J, Rey Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini Madry, M |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016); 20161025-20161028; Berlin; DOCPO20-1183 /20161010/ |
DOI: | 10.3205/16dkou659 |
Popis: | Objectives: Direct administration of therapeutic candidate gene sequences using the safe and effective recombinant adeno-associated virus (rAAV) vectors is a promising strategy to stimulate the biologic activities of articular chondrocytes as an adapted tool to treat human osteoarthritic (OA) cartilage.[for full text, please go to the a.m. URL] Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016) |
Databáze: | OpenAIRE |
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