Remodeling human osteoarthritic articular cartilage rAAV-mediated via combined gene transfer and overexpression of TGF-beta and sox9

Autor: Tao, K, Frisch, J, Rey Rico, A, Venkatesan, JK, Schmitt, G, Madry, H, Lin, JH, Cucchiarini Madry, M
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016); 20161025-20161028; Berlin; DOCPO20-1183 /20161010/
DOI: 10.3205/16dkou659
Popis: Objectives: Direct administration of therapeutic candidate gene sequences using the safe and effective recombinant adeno-associated virus (rAAV) vectors is a promising strategy to stimulate the biologic activities of articular chondrocytes as an adapted tool to treat human osteoarthritic (OA) cartilage.[for full text, please go to the a.m. URL]
Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2016)
Databáze: OpenAIRE