Bronchiolitis obliterans organising pneumonia and primary biliary cirrhosis-like lung involvement in a patient with primary biliary cirrhosis

Autor: E S Strobel, H E Schaefer, R B Bonnet, P Werner, Hans-Hartmut Peter
Rok vydání: 1998
Předmět:
Zdroj: Clinical Rheumatology. 17:246-249
ISSN: 1434-9949
0770-3198
DOI: 10.1007/bf01451058
Popis: A 55-year-old woman with a 6-year history of primary biliary cirrhosis presented with an acute onset of fever, dyspnoea, crackles over both lower lung fields, and diffuse interstitial and bibasilar patchy pulmonary opacities. After exclusion of an infectious aetiology, an open lung biopsy was performed which revealed two histopathological features: (1) bronchiolitis obliterans organising pneumonia and (2) lympho-histiocytic interstitial pneumonitis and destructive bronchiolitis. Treatment response to corticosteroids and azathioprine followed a bimodal pattern with immediate resolution of her initial presenting symptoms and late resolution of residual gas exchange defects.
Databáze: OpenAIRE