Effects of intraventricularly injected anti-brain antibodies on delayed alteration and visual discrimination tests performance in rhesus monkeys
Autor: | I. Divac, Dafina Milošević, Branislav D. Janković, Lj. Mihailović, Kosana Mitrovic |
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Rok vydání: | 1969 |
Předmět: |
medicine.medical_specialty
Time Factors Audiology Hippocampus Antibodies Developmental psychology Discrimination Learning Discrimination Psychological Developmental Neuroscience Memory medicine Animals Injections Spinal Delayed alternation Behavior Animal biology Brain Gamma globulin Haplorhini Neurology Visual discrimination Visual Perception biology.protein gamma-Globulins Caudate Nucleus Antibody Psychology |
Zdroj: | Experimental Neurology. 24:325-336 |
ISSN: | 0014-4886 |
DOI: | 10.1016/0014-4886(69)90025-9 |
Popis: | Thirteen rhesus monkeys were trained to perform delayed alternation and visual discrimination tasks and intraventricular cannulas were implanted. The animals were divided in three groups: injected with anti-caudate nucleus; antihippocampal; and normal gamma globulin, respectively. They were then tested for retention. The anti-caudate and anti-hippocampal groups were significantly impaired in the delayed alternation performance as compared to the nromal gamma globulin group. The impairment was temporary. No group was impaired on visual discrimination presented along the delayed alternation task. |
Databáze: | OpenAIRE |
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