Effects of intraventricularly injected anti-brain antibodies on delayed alteration and visual discrimination tests performance in rhesus monkeys

Autor: I. Divac, Dafina Milošević, Branislav D. Janković, Lj. Mihailović, Kosana Mitrovic
Rok vydání: 1969
Předmět:
Zdroj: Experimental Neurology. 24:325-336
ISSN: 0014-4886
DOI: 10.1016/0014-4886(69)90025-9
Popis: Thirteen rhesus monkeys were trained to perform delayed alternation and visual discrimination tasks and intraventricular cannulas were implanted. The animals were divided in three groups: injected with anti-caudate nucleus; antihippocampal; and normal gamma globulin, respectively. They were then tested for retention. The anti-caudate and anti-hippocampal groups were significantly impaired in the delayed alternation performance as compared to the nromal gamma globulin group. The impairment was temporary. No group was impaired on visual discrimination presented along the delayed alternation task.
Databáze: OpenAIRE