Exercise-induced endotoxemia: the effect of ascorbic acid supplementation
Autor: | John R. Peters, Jane McEneny, Catherine J. van Blerk, Gareth W. Davison, Christopher C. Rowlands, Simon K. Jackson, Ian S. Young, Tony Ashton, Eleri Jones |
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Rok vydání: | 2003 |
Předmět: |
Adult
Lipopolysaccharides Male Xanthine Oxidase medicine.medical_specialty Time Factors Antioxidant Adolescent Free Radicals medicine.medical_treatment Arbitrary unit Ascorbic Acid Nitric Oxide medicine.disease_cause Biochemistry Antioxidants Nitric oxide chemistry.chemical_compound Physiology (medical) Internal medicine medicine Humans Aerobic exercise Nitrite Exercise Nitrites Ascorbic acid Endotoxemia Oxidative Stress Endocrinology chemistry Dietary Supplements Gastrointestinal function Oxidative stress |
Zdroj: | Free Radical Biology and Medicine. 35:284-291 |
ISSN: | 0891-5849 |
DOI: | 10.1016/s0891-5849(03)00309-5 |
Popis: | Strenuous, long-duration aerobic exercise results in endotoxemia due to increased plasma levels of lipopolysaccharide (LPS) leading to cytokine release, oxidative stress, and altered gastrointestinal function. However, the effect of short-term strenuous aerobic exercise either with or without antioxidant supplementation on exercise-induced endotoxemia is unknown. A significant increase in the concentration of bacterial LPS (endotoxin) was noted in the venous circulation of healthy volunteers following maximal acute aerobic exercise (0.14(-1) pre-exercise vs. 0.24(-1) postexercise, p |
Databáze: | OpenAIRE |
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