Exercise-induced endotoxemia: the effect of ascorbic acid supplementation

Autor: John R. Peters, Jane McEneny, Catherine J. van Blerk, Gareth W. Davison, Christopher C. Rowlands, Simon K. Jackson, Ian S. Young, Tony Ashton, Eleri Jones
Rok vydání: 2003
Předmět:
Zdroj: Free Radical Biology and Medicine. 35:284-291
ISSN: 0891-5849
DOI: 10.1016/s0891-5849(03)00309-5
Popis: Strenuous, long-duration aerobic exercise results in endotoxemia due to increased plasma levels of lipopolysaccharide (LPS) leading to cytokine release, oxidative stress, and altered gastrointestinal function. However, the effect of short-term strenuous aerobic exercise either with or without antioxidant supplementation on exercise-induced endotoxemia is unknown. A significant increase in the concentration of bacterial LPS (endotoxin) was noted in the venous circulation of healthy volunteers following maximal acute aerobic exercise (0.14(-1) pre-exercise vs. 0.24(-1) postexercise, p
Databáze: OpenAIRE