Epstein-Barr Virus Associated Smooth Muscle Tumors in Post Transplant Pediatric Patients Two Cases of Rare Locations, and Review of the Literature
| Autor: | Carlos R. Abramowsky, Nancy Elawabdeh, Maaman Z. Bashir, David M. Wrubel, Brent M. Cone, Hans E. Grossniklaus, Bahig M. Shehata, Joseph D. Walrath |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Epstein-Barr Virus Infections
Pathology medicine.medical_specialty Adolescent medicine.medical_treatment Neoplastic transformations Liver transplantation medicine.disease_cause Organ transplantation Virus Pathology and Forensic Medicine Lesion Immunocompromised Host Postoperative Complications hemic and lymphatic diseases medicine Humans Child Leiomyoma business.industry General Medicine Epstein–Barr virus Post transplant Liver Transplantation Colonic Neoplasms Pediatrics Perinatology and Child Health Smooth Muscle Tumor Immunology Orbital Neoplasms Female medicine.symptom business |
| Zdroj: | Fetal and Pediatric Pathology. 32:184-191 |
| ISSN: | 1551-3823 1551-3815 |
| DOI: | 10.3109/15513815.2012.701265 |
| Popis: | Epstein-Barr virus (EBV) may present few or no symptoms in immunocompetent individuals; however, in immunocompromised patients as in the case of AIDS and post-transplant patients, the virus occasionally stimulates neoplastic transformations. Epstein-Barr virus may play a role in the development of smooth muscle tumors (SMT). In the case of Epstein-Barr associated smooth muscle tumors (EBV+SMT), the virus is thought to be the leading factor to the tumorigenic pathway. We report two pediatric patients (6 and 13 years old) who underwent liver transplantation and developed EBV+SMT in the colon and orbit. These two cases represent rare locations for this kind of lesion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |