A novel BCR-ABL fusion transcript (e15a2) in 2 patients with atypical chronic myeloproliferative syndrome

Autor: María Moreno, Marı́a del Rosario Uriarte, Rossana Bonomi, Adriana Cardeza, Marı́a Noel Cortinas
Rok vydání: 2001
Předmět:
Zdroj: Blood. 97:3668-3669
ISSN: 1528-0020
0006-4971
DOI: 10.1182/blood.v97.11.3668
Popis: The BCR-ABL chimeric gene results from a reciprocal translocation, t(9;22)(q34;q11). The breakpoint on chromosome 9 is in the majority of cases 5′ to ABL exon 2, whereas the breakpoints on chromosome 22 can occur in various regions within the BCR gene, giving rise to different BCR-ABL junction
Databáze: OpenAIRE