A novel BCR-ABL fusion transcript (e15a2) in 2 patients with atypical chronic myeloproliferative syndrome
Autor: | María Moreno, Marı́a del Rosario Uriarte, Rossana Bonomi, Adriana Cardeza, Marı́a Noel Cortinas |
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Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Blood. 97:3668-3669 |
ISSN: | 1528-0020 0006-4971 |
DOI: | 10.1182/blood.v97.11.3668 |
Popis: | The BCR-ABL chimeric gene results from a reciprocal translocation, t(9;22)(q34;q11). The breakpoint on chromosome 9 is in the majority of cases 5′ to ABL exon 2, whereas the breakpoints on chromosome 22 can occur in various regions within the BCR gene, giving rise to different BCR-ABL junction |
Databáze: | OpenAIRE |
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