In Situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing

Autor: Patrick W. Cooley, Bogdan V. Antohe
Rok vydání: 2007
Předmět:
Zdroj: Microarrays ISBN: 9781588295897
DOI: 10.1007/978-1-59745-303-5_15
Popis: The study of protein-protein and protein-DNA interactions is critical to understand biological processes. This article presents the methodology to create peptide microarrays in situ for the high-throughput screening of complex biomolecules. The in situ ink-jet peptide synthesis results in a conservation of costly reagent and amino acids, whereas providing a means to produce denser peptide arrays. A smaller amount of test sample is required to observe interaction when using these high-density peptide arrays.
Databáze: OpenAIRE
načítá se...