In Situ Synthesis of Peptide Microarrays Using Ink-Jet Microdispensing

Autor:	Patrick W. Cooley, Bogdan V. Antohe
Rok vydání:	2007
Předmět:	chemistry.chemical_classification In situ chemistry.chemical_compound chemistry Biomolecule Reagent Peptide synthesis Peptide DNA microarray Combinatorial chemistry Test sample Amino acid
Zdroj:	Microarrays ISBN: 9781588295897
DOI:	10.1007/978-1-59745-303-5_15
Popis:	The study of protein-protein and protein-DNA interactions is critical to understand biological processes. This article presents the methodology to create peptide microarrays in situ for the high-throughput screening of complex biomolecules. The in situ ink-jet peptide synthesis results in a conservation of costly reagent and amino acids, whereas providing a means to produce denser peptide arrays. A smaller amount of test sample is required to observe interaction when using these high-density peptide arrays.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f2fdb96686549d14aa07d65f9e783ac7 https://doi.org/10.1007/978-1-59745-303-5_15 Zobrazit plný text záznamu