Four meroterpenoids from Alternaria alternata isolated from Paeonia lactiflora
Autor: | Guo-Kai Wang, Ju-Tao Wang, Lin Chen, Jin-Song Liu, Gang Wang, Zong-Hui Ma, Feng-Qing Xu, Yang Yu |
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Rok vydání: | 2019 |
Předmět: |
Paeonia lactiflora
Chromatography biology 010405 organic chemistry Chemistry Tumor cells Plant Science biology.organism_classification 01 natural sciences Biochemistry Alternaria alternata 0104 chemical sciences 010404 medicinal & biomolecular chemistry Fermentation broth Agronomy and Crop Science Biotechnology |
Zdroj: | Phytochemistry Letters. 31:1-4 |
ISSN: | 1874-3900 |
DOI: | 10.1016/j.phytol.2019.03.001 |
Popis: | Four new natural meroterpenoids, tricycloalternarenes (TCAs)15b‒18b (1‒4) along with four known TCAs (5‒8) have been isolated from the fermentation broth of Alternaria alternata derived from Paeonia lactiflora. The structures of compounds 1‒4 were elucidated by in-depth analyses of NMR spectra, HRESIMS and optical rotation experiments. Cytotoxic activities of 1‒4 against five selected tumor cell lines were evaluated. |
Databáze: | OpenAIRE |
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