Four meroterpenoids from Alternaria alternata isolated from Paeonia lactiflora

Autor: Guo-Kai Wang, Ju-Tao Wang, Lin Chen, Jin-Song Liu, Gang Wang, Zong-Hui Ma, Feng-Qing Xu, Yang Yu
Rok vydání: 2019
Předmět:
Zdroj: Phytochemistry Letters. 31:1-4
ISSN: 1874-3900
DOI: 10.1016/j.phytol.2019.03.001
Popis: Four new natural meroterpenoids, tricycloalternarenes (TCAs)15b‒18b (1‒4) along with four known TCAs (5‒8) have been isolated from the fermentation broth of Alternaria alternata derived from Paeonia lactiflora. The structures of compounds 1‒4 were elucidated by in-depth analyses of NMR spectra, HRESIMS and optical rotation experiments. Cytotoxic activities of 1‒4 against five selected tumor cell lines were evaluated.
Databáze: OpenAIRE