Vasoactive intestinal peptide and bipolar affective illness

Autor: Peter Hotvedt, Wade H. Berrettini, Susan Simmons-Alling, Elliot S. Gershon, John I. Nurnberger
Rok vydání: 1985
Předmět:
Zdroj: Journal of Affective Disorders. 8:55-59
ISSN: 0165-0327
DOI: 10.1016/0165-0327(85)90072-2
Popis: In an attempt to evaluate the role of VIP in affective disorder, measurements of lymphocyte VIP receptors, and plasma and CSF VIP levels were made in unmedicated and lithium-treated euthymic bipolars and controls. Lithium decreased plasma (P=0.01) and CSF (P=0.05) VIP levels and increased the affinity (decreased the KD) of the VIP lymphocyte receptor (P
Databáze: OpenAIRE