Vasoactive intestinal peptide and bipolar affective illness
Autor: | Peter Hotvedt, Wade H. Berrettini, Susan Simmons-Alling, Elliot S. Gershon, John I. Nurnberger |
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Rok vydání: | 1985 |
Předmět: |
medicine.medical_specialty
Lithium (medication) business.industry Lymphocyte medicine.medical_treatment Vasoactive intestinal peptide Psychiatry and Mental health Clinical Psychology VIP Receptors Endocrinology medicine.anatomical_structure Cerebrospinal fluid Internal medicine Blood plasma medicine business Receptor Antipsychotic hormones hormone substitutes and hormone antagonists medicine.drug |
Zdroj: | Journal of Affective Disorders. 8:55-59 |
ISSN: | 0165-0327 |
DOI: | 10.1016/0165-0327(85)90072-2 |
Popis: | In an attempt to evaluate the role of VIP in affective disorder, measurements of lymphocyte VIP receptors, and plasma and CSF VIP levels were made in unmedicated and lithium-treated euthymic bipolars and controls. Lithium decreased plasma (P=0.01) and CSF (P=0.05) VIP levels and increased the affinity (decreased the KD) of the VIP lymphocyte receptor (P |
Databáze: | OpenAIRE |
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