Specific binding of triiodothyronine to the nucleoplasm

Autor: A. T. Adylova, Ya. Kh. Turakulov
Rok vydání: 1997
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 123:190-192
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02766449
Popis: The study of the binding of thyroid hormones to the nucleoplasm demonstrates the presence of triiodothyronine-binding molecules characterized by high affinity and limited binding capacity. The binding of thyroid analogs correlates with their thyromimetic activity. Sucrose gradient ultracentrifugation of triiodothyronine-labeled nuclear extract reveals the presence of triiodothyronine receptors, ribonucleoprotein particles with a sedimentation coefficient about 30S.
Databáze: OpenAIRE