Specific binding of triiodothyronine to the nucleoplasm
Autor: | A. T. Adylova, Ya. Kh. Turakulov |
---|---|
Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 123:190-192 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf02766449 |
Popis: | The study of the binding of thyroid hormones to the nucleoplasm demonstrates the presence of triiodothyronine-binding molecules characterized by high affinity and limited binding capacity. The binding of thyroid analogs correlates with their thyromimetic activity. Sucrose gradient ultracentrifugation of triiodothyronine-labeled nuclear extract reveals the presence of triiodothyronine receptors, ribonucleoprotein particles with a sedimentation coefficient about 30S. |
Databáze: | OpenAIRE |
Externí odkaz: |