Third Trimester Fetal Heart Rates in Antibody-Mediated Complete Heart Block Predict Need for Neonatal Pacemaker Placement

Autor: John C. Wood, Michael J. Silka, Justin Pick, Mark Shwayder, Jay D. Pruetz, Yaniv Bar-Cohen, Allison C. Hill
Rok vydání: 2021
Předmět:
Zdroj: Pediatric Cardiology. 43:324-331
ISSN: 1432-1971
0172-0643
DOI: 10.1007/s00246-021-02723-w
Popis: Congenital complete heart block (CCHB) affects 1 in 20,000 newborns. This study evaluates fetal and neonatal risk factors predictive of neonatal pacemaker placement in antibody-mediated complete heart block. The Children’s Hospital Los Angeles institutional fetal, pacemaker, and medical record databases were queried for confirmed SSA/SSB cases of CCHB between January 2004 and July 2019. Cases excluded were those with a diagnosis beyond the neonatal period, diagnosis of a channelopathy, or if maternal antibody status was unknown. We recorded the gestational age (GA), birth weight (BW), fetal heart rates (FHRs) of the last echocardiogram before delivery, specific neonatal ECG and echocardiogram findings, age at pacemaker placement, and mortality. Of 43 neonates identified with CCHB, 27 had confirmed maternal antibody exposure. Variables associated with neonatal pacemaker implantation were FHRs
Databáze: OpenAIRE