Third Trimester Fetal Heart Rates in Antibody-Mediated Complete Heart Block Predict Need for Neonatal Pacemaker Placement
Autor: | John C. Wood, Michael J. Silka, Justin Pick, Mark Shwayder, Jay D. Pruetz, Yaniv Bar-Cohen, Allison C. Hill |
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Rok vydání: | 2021 |
Předmět: |
Bradycardia
medicine.medical_specialty medicine.diagnostic_test Heart block business.industry Birth weight Gestational age Prenatal diagnosis medicine.disease Cardiac surgery Internal medicine Pediatrics Perinatology and Child Health medicine Cardiology Pacemaker Placement medicine.symptom Cardiology and Cardiovascular Medicine business Fetal echocardiography |
Zdroj: | Pediatric Cardiology. 43:324-331 |
ISSN: | 1432-1971 0172-0643 |
DOI: | 10.1007/s00246-021-02723-w |
Popis: | Congenital complete heart block (CCHB) affects 1 in 20,000 newborns. This study evaluates fetal and neonatal risk factors predictive of neonatal pacemaker placement in antibody-mediated complete heart block. The Children’s Hospital Los Angeles institutional fetal, pacemaker, and medical record databases were queried for confirmed SSA/SSB cases of CCHB between January 2004 and July 2019. Cases excluded were those with a diagnosis beyond the neonatal period, diagnosis of a channelopathy, or if maternal antibody status was unknown. We recorded the gestational age (GA), birth weight (BW), fetal heart rates (FHRs) of the last echocardiogram before delivery, specific neonatal ECG and echocardiogram findings, age at pacemaker placement, and mortality. Of 43 neonates identified with CCHB, 27 had confirmed maternal antibody exposure. Variables associated with neonatal pacemaker implantation were FHRs |
Databáze: | OpenAIRE |
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