Are Drug–Drug Interactions The Smoking Guns of Local Anesthetic Toxicity? Smoking Gun I
Autor: | L. Michele Noles |
---|---|
Rok vydání: | 2015 |
Předmět: | |
Zdroj: | A Case Approach to Perioperative Drug-Drug Interactions ISBN: 9781461474944 |
DOI: | 10.1007/978-1-4614-7495-1_41 |
Popis: | This case discusses a pharmacokinetic interaction between ropivacaine and fluoxetine. Ropivacaine is a cytochrome P450 3A4 and cytochrome 1A2 substrate. Fluoxetine is an inhibitor of both enzymes. Coadministration may result in ropivacaine toxicity. |
Databáze: | OpenAIRE |
Externí odkaz: |
načítá se...