Diffuse primary extra-gastrointestinal stromal tumor of the peritoneum
| Autor: | Liang-Ji Lu, Fei Dong, Xiao-Pei Xu, Jie Min |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Abdominal pain Gastrointestinal tract business.industry Imatinib General Medicine 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Imatinib mesylate Peritoneum 030220 oncology & carcinogenesis Medicine Immunohistochemistry 030212 general & internal medicine Radiology Differential diagnosis Stromal tumor medicine.symptom business medicine.drug |
| Zdroj: | Medicine. 99:e22493 |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000022493 |
| Popis: | Rationale Gastrointestinal stromal tumors that present outside the gastrointestinal tract are known for extra-gastrointestinal stromal tumors (EGISTs) and they share the same morphological and immunohistochemical characteristics with gastrointestinal stromal tumors. Here we report a rare case of diffuse primary EGIST arising at peritoneum. Patient concerns A 57-year-old male presented to the hospital with abdominal pain and right lower abdominal tenderness. Diagnosis The core needle puncture biopsy showed epithelial-like cells and the nuclei were ovoid and focally elongated. Immunohistochemical examination was consistent with a primary EGIST of the peritoneum. Interventions The patient was treated with Imatinib mesylate. Outcomes Five months later, there is no complication resulting from treatment. The follow-up abdominal contrast-enhanced CT showed the lesion was significantly decreased in size, and was evaluated as partial response. The patient continued the treatment with Imatinib as prescribed by the oncologist. Lessons EGISTs are rare and should be considered in the differential diagnosis of the peritoneal tumors and immunohistochemistry helps to confirm the diagnosis. Further study with longer follow-up is desired to characterize these uncommon tumors. |
| Databáze: | OpenAIRE |
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