Cholesterin - ein Marker für multiple Risikofaktoren? - Ein Vergleich zwischen Koronarkranken und -gesunden
| Autor: | Regeniter A, Martin Kaltenbach, Siekmeier R, Kaiser B, Rose Dm, Schneider W, Winkelmann Br |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Cholesterol business.industry Increased total cholesterol General Medicine Coronary disease medicine.disease Multiple risk factors Gastroenterology Coronary artery disease chemistry.chemical_compound Older patients chemistry Total cholesterol Internal medicine medicine In patient business |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 117:1390-1393 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-2008-1062455 |
| Popis: | Comparison was made in a cross-sectional study between 658 patients in whom coronary arteriography had shown (n = 304) or excluded coronary artery disease (CHD) (n = 354) and a clinically healthy group as controls (n = 1658), to assess possible risk factors. Patients aged 31-40 years with CHD had the highest total cholesterol levels (286 +/- 43 mg/dl) and the highest number of risk factors (3.6 +/- 0.9) compared to patients without CHD of the same age (204 +/- 30 mg/dl; 2.0 +/- 0.5) and healthy controls (216 +/- 45 mg/dl; 1.7 +/- 0.5) (P less than 0.001). In older patients with CHD, total cholesterol levels were lower (age group 61-70 years: 231 +/- 49 mg/dl), reaching about the same level as that of patients without CHD (232 +/- 54 mg/dl) or healthy controls of the same age (228 +/- 55 mg/dl). Furthermore, it was demonstrated that increased total cholesterol concentration can indicate the presence of other risk factors. It would thus appear that the level of total cholesterol in patients with CHD is decisively influenced by age and the presence of other risk factors. |
| Databáze: | OpenAIRE |
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