Cholesterin - ein Marker für multiple Risikofaktoren? - Ein Vergleich zwischen Koronarkranken und -gesunden

Autor: Regeniter A, Martin Kaltenbach, Siekmeier R, Kaiser B, Rose Dm, Schneider W, Winkelmann Br
Rok vydání: 2008
Předmět:
Zdroj: DMW - Deutsche Medizinische Wochenschrift. 117:1390-1393
ISSN: 1439-4413
0012-0472
DOI: 10.1055/s-2008-1062455
Popis: Comparison was made in a cross-sectional study between 658 patients in whom coronary arteriography had shown (n = 304) or excluded coronary artery disease (CHD) (n = 354) and a clinically healthy group as controls (n = 1658), to assess possible risk factors. Patients aged 31-40 years with CHD had the highest total cholesterol levels (286 +/- 43 mg/dl) and the highest number of risk factors (3.6 +/- 0.9) compared to patients without CHD of the same age (204 +/- 30 mg/dl; 2.0 +/- 0.5) and healthy controls (216 +/- 45 mg/dl; 1.7 +/- 0.5) (P less than 0.001). In older patients with CHD, total cholesterol levels were lower (age group 61-70 years: 231 +/- 49 mg/dl), reaching about the same level as that of patients without CHD (232 +/- 54 mg/dl) or healthy controls of the same age (228 +/- 55 mg/dl). Furthermore, it was demonstrated that increased total cholesterol concentration can indicate the presence of other risk factors. It would thus appear that the level of total cholesterol in patients with CHD is decisively influenced by age and the presence of other risk factors.
Databáze: OpenAIRE
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