Late onset of cerebellar cortical degeneration in a Magellanic penguin (Spheniscus magellanicus)
| Autor: | Marianthi Ioannidis, Chiho Kezuka, Jyoji Yamate, Miyuu Tanaka, Mitsuru Kuwamura, Sayaka Yasui, Tetsuya Hasegawa, Takeshi Izawa, Maremichi Oyamada |
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| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty Air sacs General Veterinary biology medicine.diagnostic_test business.industry Neurodegeneration Late onset Magnetic resonance imaging Spheniscus magellanicus biology.organism_classification medicine.disease people.cause_of_death Calbindin nervous system Cerebellar cortex Medicine business people Cerebellar abiotrophy |
| Zdroj: | Journal of Veterinary Medical Science. 81:750-752 |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.19-0089 |
| Popis: | An 8-year-old female Magellanic penguin (Spheniscus magellanicus) started to show epilepsy-like seizures. Subsequent magnetic resonance imaging (MRI) examinations did not reveal any responsible lesions. The neurological symptoms worsened at the age of 10. This penguin became recumbent and died 6 months later after the apparition of the recumbency. At necropsy, only multiple yellowish necrotic lesions in the air sacs and lungs were found. Histopathological evaluation of the brain showed a marked loss of Purkinje cells and many hypertrophied parvalbumin-positive basket/stellate cells were seen in the cerebellar cortex. Calbindin immunohistochemistry demonstrated disrupted arrangement of dendrites in the Purkinje cells. This case was diagnosed as cerebellar cortical degeneration with a very late onset and a slow progression in a Magellanic penguin. |
| Databáze: | OpenAIRE |
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