Depletion of antioxidants is associated with no-reflow phenomenon in acute myocardial infarction
| Autor: | Hideyuki Takaoka, Hidenari Matsumoto, Nobutaka Inoue, Toru Ozawa, Satoshi Watanabe, Hiroyuki Masai, Toshiro Shinke, Katsuya Hata, Ryohei Yoshikawa, Mitsuhiro Yokoyama |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Vitamin E Percutaneous coronary intervention General Medicine medicine.disease medicine.disease_cause Coronary circulation medicine.anatomical_structure Internal medicine Conventional PCI No reflow phenomenon cardiovascular system medicine Cardiology cardiovascular diseases Myocardial infarction Cardiology and Cardiovascular Medicine business TIMI Oxidative stress |
| Zdroj: | Clinical Cardiology. 27:466-470 |
| ISSN: | 0160-9289 |
| DOI: | 10.1002/clc.4960270809 |
| Popis: | Background: No-reflow phenomenon is observed in approximately one-third of patients after percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI), and is associated with poor functional and clinical outcomes. On the other hand, the formation of free radicals in vasculature exerts deleterious effects on coronary microcirculation. Hypothesis: We hypothesized that redox state in coronary circulation may play a crucial role in no-reflow phenomenon in AMI. Methods: Consecutive 26 patients with first AMI who underwent primary PCI |
| Databáze: | OpenAIRE |
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