Depletion of antioxidants is associated with no-reflow phenomenon in acute myocardial infarction

Autor: Hideyuki Takaoka, Hidenari Matsumoto, Nobutaka Inoue, Toru Ozawa, Satoshi Watanabe, Hiroyuki Masai, Toshiro Shinke, Katsuya Hata, Ryohei Yoshikawa, Mitsuhiro Yokoyama
Rok vydání: 2004
Předmět:
Zdroj: Clinical Cardiology. 27:466-470
ISSN: 0160-9289
DOI: 10.1002/clc.4960270809
Popis: Background: No-reflow phenomenon is observed in approximately one-third of patients after percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI), and is associated with poor functional and clinical outcomes. On the other hand, the formation of free radicals in vasculature exerts deleterious effects on coronary microcirculation. Hypothesis: We hypothesized that redox state in coronary circulation may play a crucial role in no-reflow phenomenon in AMI. Methods: Consecutive 26 patients with first AMI who underwent primary PCI
Databáze: OpenAIRE
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