Effect of structure of polar head of phospholipids on their fragmentation during γ-irradiation of model membranes
Autor: | Oleg I. Shadyro, M. A. Kisel, I. L. Yurkova, Juergen Arnhold |
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Rok vydání: | 2006 |
Předmět: | |
Zdroj: | High Energy Chemistry. 40:300-303 |
ISSN: | 1608-3148 0018-1439 |
DOI: | 10.1134/s0018143906050031 |
Popis: | The ability of phospholipids with different structures of the polar head (phosphatidylpropandiol, phosphatidylglycerol, phosphatidylinositol, and cardiolipin) to sustain radiation-induced fragmentation was studied. It was shown by thin-layer chromatography and MALDI-TOF mass spectroscopy that all test lipids entering the composition of model membranes subjected to γ-irradiation suffered fragmentation yielding phosphatidic acid. The radiation-chemical yield of phosphatidic acid increased in this phospholipid series on passing from phosphatidylpropanediol to cardiolipin. |
Databáze: | OpenAIRE |
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