Effect of structure of polar head of phospholipids on their fragmentation during γ-irradiation of model membranes

Autor: Oleg I. Shadyro, M. A. Kisel, I. L. Yurkova, Juergen Arnhold
Rok vydání: 2006
Předmět:
Zdroj: High Energy Chemistry. 40:300-303
ISSN: 1608-3148
0018-1439
DOI: 10.1134/s0018143906050031
Popis: The ability of phospholipids with different structures of the polar head (phosphatidylpropandiol, phosphatidylglycerol, phosphatidylinositol, and cardiolipin) to sustain radiation-induced fragmentation was studied. It was shown by thin-layer chromatography and MALDI-TOF mass spectroscopy that all test lipids entering the composition of model membranes subjected to γ-irradiation suffered fragmentation yielding phosphatidic acid. The radiation-chemical yield of phosphatidic acid increased in this phospholipid series on passing from phosphatidylpropanediol to cardiolipin.
Databáze: OpenAIRE