A Facile Solvent-Free Synthesis of High Specific Activity Potassium [14C]Formate and Ethyl [14C]Formate Under Microwave Irradiation

Autor:	Sivaprasad Nagalingam, Mathew Kudulil Mathai, Ravi Seshan, Parameshwaran Vadakke Kodara Unny
Rok vydání:	2006
Předmět:	010405 organic chemistry Cyanide Potassium Inorganic chemistry chemistry.chemical_element General Chemistry 010402 general chemistry Alkali metal 01 natural sciences Ampoule 0104 chemical sciences chemistry.chemical_compound Hydrolysis chemistry Formate Irradiation Microwave
Zdroj:	Journal of Chemical Research. 2006:27-28
ISSN:	2047-6507 1747-5198
DOI:	10.3184/030823406776331124
Popis:	Potassium [14C]cyanide was first hydrolysed to potassium [14C]formate with dilute alkali under microwave (1300 W) irradiation for 8 min in a sealed glass ampoule. Potassium [14C]formate was then esterified with triethyl orthophosphate under microwave irradiation for 20 min to furnish ethyl [14C]formate having high specific radioactivity (50 mCi/mmol) in an yield of 98%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4de5001800a1c5a40a7be456c2210e23 https://doi.org/10.3184/030823406776331124 Zobrazit plný text záznamu