A Facile Solvent-Free Synthesis of High Specific Activity Potassium [14C]Formate and Ethyl [14C]Formate Under Microwave Irradiation
Autor: | Sivaprasad Nagalingam, Mathew Kudulil Mathai, Ravi Seshan, Parameshwaran Vadakke Kodara Unny |
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Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Journal of Chemical Research. 2006:27-28 |
ISSN: | 2047-6507 1747-5198 |
DOI: | 10.3184/030823406776331124 |
Popis: | Potassium [14C]cyanide was first hydrolysed to potassium [14C]formate with dilute alkali under microwave (1300 W) irradiation for 8 min in a sealed glass ampoule. Potassium [14C]formate was then esterified with triethyl orthophosphate under microwave irradiation for 20 min to furnish ethyl [14C]formate having high specific radioactivity (50 mCi/mmol) in an yield of 98%. |
Databáze: | OpenAIRE |
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