Understanding the Anatomic Basis for Obstructive Sleep Apnea Syndrome in Adolescents

Autor: Joel Traylor, Brendan T. Keenan, Francois-Louis Comyn, Richard Schwab, Ruth Bradford, Carole L. Marcus, Drew A. Torigian, Christopher Kim, Ignacio E. Tapia, Sheila Bagchi, Shirley Huang, Stephen Wang
Rok vydání: 2015
Předmět:
Zdroj: American Journal of Respiratory and Critical Care Medicine. 191:1295-1309
ISSN: 1535-4970
1073-449X
DOI: 10.1164/rccm.201501-0169oc
Popis: Rationale: Structural risk factors for obstructive sleep apnea syndrome (OSAS) in adolescents have not been well characterized. Because many adolescents with OSAS are obese, we hypothesized that the anatomic OSAS risk factors would be more similar to those in adults than those in children.Objectives: To investigate the anatomic risk factors in adolescents with OSAS compared with obese and lean control subjects using magnetic resonance imaging (MRI).Methods: Three groups of adolescents (age range: 12–16 yr) underwent MRI: obese individuals with OSAS (n = 49), obese control subjects (n = 38), and lean control subjects (n = 50).Measurements and Main Results: We studied 137 subjects and found that (1) obese adolescents with OSAS had increased adenotonsillar tissue compared with obese and lean control subjects; (2) obese OSAS adolescents had a smaller nasopharyngeal airway than control subjects; (3) the size of other upper airway soft tissue structures (volume of the tongue, parapharyngeal fat pads, lateral wa...
Databáze: OpenAIRE
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