Understanding the Anatomic Basis for Obstructive Sleep Apnea Syndrome in Adolescents
| Autor: | Joel Traylor, Brendan T. Keenan, Francois-Louis Comyn, Richard Schwab, Ruth Bradford, Carole L. Marcus, Drew A. Torigian, Christopher Kim, Ignacio E. Tapia, Sheila Bagchi, Shirley Huang, Stephen Wang |
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| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pediatrics medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_device Sleep apnea Soft tissue Magnetic resonance imaging Critical Care and Intensive Care Medicine medicine.disease Adenoid Nasopharyngeal airway respiratory tract diseases Obstructive sleep apnea medicine.anatomical_structure Tongue medicine Physical therapy business Airway |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 191:1295-1309 |
| ISSN: | 1535-4970 1073-449X |
| DOI: | 10.1164/rccm.201501-0169oc |
| Popis: | Rationale: Structural risk factors for obstructive sleep apnea syndrome (OSAS) in adolescents have not been well characterized. Because many adolescents with OSAS are obese, we hypothesized that the anatomic OSAS risk factors would be more similar to those in adults than those in children.Objectives: To investigate the anatomic risk factors in adolescents with OSAS compared with obese and lean control subjects using magnetic resonance imaging (MRI).Methods: Three groups of adolescents (age range: 12–16 yr) underwent MRI: obese individuals with OSAS (n = 49), obese control subjects (n = 38), and lean control subjects (n = 50).Measurements and Main Results: We studied 137 subjects and found that (1) obese adolescents with OSAS had increased adenotonsillar tissue compared with obese and lean control subjects; (2) obese OSAS adolescents had a smaller nasopharyngeal airway than control subjects; (3) the size of other upper airway soft tissue structures (volume of the tongue, parapharyngeal fat pads, lateral wa... |
| Databáze: | OpenAIRE |
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