Associations of Vitamin D Level and Glucoregulatory Parameters in Type 2 Diabetes Mellitus
Autor: | Damir Benc, Borislav Tapavički, Mina Maricic, Andrea Zubnar, Nebojsa Janjic, Aleksandra Popović, Stanislava Nikolic, Danijel Slavic, Dea Karaba Jakovljević |
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Rok vydání: | 2022 |
Předmět: |
medicine.medical_specialty
endocrine system diseases business.industry nutritional and metabolic diseases Type 2 Diabetes Mellitus 030209 endocrinology & metabolism General Medicine 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Endocrinology Internal medicine Vitamin D and neurology Medicine business |
Zdroj: | Serbian Journal of Experimental and Clinical Research. 23:141-146 |
ISSN: | 2335-075X 1820-8665 |
DOI: | 10.2478/sjecr-2019-0054 |
Popis: | Vitamin D is known to affect the functions of pancreatic beta cells, but the effects of vitamin D deficiency on glucoregulatory mechanisms are still inconclusive. The aim of this study was to link vitamin D levels with parameters of insulin resistance and insulin secretion. The study included 70 male and female participants, 40 newly diagnosed patients with type 2 diabetes mellitus (T2DM) and 30 healthy controls. All participants were tested for fasting glucose, hemoglobin A1c, fasting insulin, vitamin D levels, and the HOMA indexes were calculated using HOMA2 calculator. Fasting glucose levels, insulinemia, hemoglobin A1c levels and HOMA IR were all significantly higher in the diabetic group (p |
Databáze: | OpenAIRE |
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