Associations of Vitamin D Level and Glucoregulatory Parameters in Type 2 Diabetes Mellitus

Autor: Damir Benc, Borislav Tapavički, Mina Maricic, Andrea Zubnar, Nebojsa Janjic, Aleksandra Popović, Stanislava Nikolic, Danijel Slavic, Dea Karaba Jakovljević
Rok vydání: 2022
Předmět:
Zdroj: Serbian Journal of Experimental and Clinical Research. 23:141-146
ISSN: 2335-075X
1820-8665
DOI: 10.2478/sjecr-2019-0054
Popis: Vitamin D is known to affect the functions of pancreatic beta cells, but the effects of vitamin D deficiency on glucoregulatory mechanisms are still inconclusive. The aim of this study was to link vitamin D levels with parameters of insulin resistance and insulin secretion. The study included 70 male and female participants, 40 newly diagnosed patients with type 2 diabetes mellitus (T2DM) and 30 healthy controls. All participants were tested for fasting glucose, hemoglobin A1c, fasting insulin, vitamin D levels, and the HOMA indexes were calculated using HOMA2 calculator. Fasting glucose levels, insulinemia, hemoglobin A1c levels and HOMA IR were all significantly higher in the diabetic group (p
Databáze: OpenAIRE