Analgesic, anti-inflammatory and anti-pyretic activities of D-3-O-methylchiroinositol isolated from stem bark of Piliostigma thonningii

Autor:	Chinaka O. Nwaehujor, Isaac Uzoma Asuzu, R. I. Udegbunam
Rok vydání:	2015
Předmět:	Stem bark Subacute phase biology Chemistry medicine.drug_class Organic Chemistry Analgesic Arthritis Anti pyretic Piliostigma thonningii Pharmacology biology.organism_classification medicine.disease Anti-inflammatory Anesthesia medicine General Pharmacology Toxicology and Pharmaceutics Paw edema
Zdroj:	Medicinal Chemistry Research. 24:4139-4145
ISSN:	1554-8120 1054-2523
DOI:	10.1007/s00044-015-1459-9
Popis:	D-3-O-methylchiroinositol isolated from the stem bark of Piliostigma thonningii was evaluated for analgesic, anti-inflammatory and anti-pyretic activities. The compound was screened for analgesic activity by the acetic acid-induced writhing and tail immersion tests. The anti-inflammatory activities were evaluated by the carrageenan-induced paw edema and Freund adjuvant-induced arthritis tests, while its anti-pyretic activity was determined using the yeast-induced pyrexia test. D-3-O-methylchiroinositol (10, 30 and 60 mg/kg) significantly (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::43fa41af3e59db76100dd6ddd3d47484 https://doi.org/10.1007/s00044-015-1459-9 Zobrazit plný text záznamu Full text from SpringerLink