A clinical trial of blood and crystalloid cardioplegia

Autor: Peter R. McLaughlin, Ronald J. Baird, Donald A.G. Mickle, Stephen E. Fremes, Reginald S. Harding, Susan J. Seawright, George T. Christakis, M. Mindy Madonik, Richard D. Weisel, JoanI vanov, Sylvain Houle
Rok vydání: 1984
Předmět:
Zdroj: The Journal of Thoracic and Cardiovascular Surgery. 88:726-741
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)35440-6
Popis: Although experimental studies suggest that blood cardioplegia provides better protection than crystalloid cardioplegia, clinical studies have been inconclusive. Ninety patients undergoing coronary bypass grafting were randomized to receive either blood (n = 43) or crystalloid cardioplegia (n = 47). The incidence of perioperative myocardial infarction was lower with blood cardioplegia (blood, n = 0; crystalloid, n = 5; p = 0.06), and the maximum MB isoenzyme of creatine kinase was significantly less with blood cardioplegia (blood, 26.3 ± 12.6 U/L; crystalloid, 35.6 ± 17.0 U/L, mean ± standard deviation; p
Databáze: OpenAIRE